Overview
Properties
Sensitivity: | < 10 pg/ml |
Storage Instructions: | Store at 4˚C for 1 month, at -20˚C for up to longer storage. Avoid multiple freeze/thaw cycles (Shipped with blue ice.) |
Kit Components
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Material Required But Not Provided
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Background
Gene Name: | VEGFR3 |
Background: | Fms - related tyrosine kinase 4, also known as FLT4 or VEGFR3, is a protein which in humans is encoded by the FLT4 gene. It is mapped to 5q35.3. This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. FLT4 has an essential role in the development of the embryonic cardiovascular system before the emergence of the lymphatic vessels. It has been found that FLT4, which provides proangiogenic signaling when expressed on endothelium, may also have antiangiogenic properties when expressed at an avascular site by nonendothelial cells. FLT4 is also regarded as a regulator of vascular network formation. |
Synonym: | FLT 4; FLT4; FLT41; Fms like tyrosine kinase 4; Fms related tyrosine kinase 4; LMPH1A; PCL; Tyrosine protein kinase receptor FLT4; Vascular endothelial growth factor receptor 3; VEGFR 3; VEGFR3 |
NCBI Gene ID: | 114110 |
UniProt ID: | Q91ZT1 |
Intra/Inter Assay Precision
Intra | Inter | |||||
Sample: | 1 | 2 | 3 | 1 | 2 | 3 |
n: | 16 | 16 | 16 | 24 | 24 | 24 |
Mean (pg/ml): | 1580 | 3021 | 6135 | 1749 | 3312 | 6758 |
Standard deviation: | 52.14 | 142 | 319 | 80.45 | 182.2 | 432.5 |
CV (%): | 3.3 | 4.7 | 5.2 | 4.6 | 5.5 | 6.4 |
Typical Data
Concentration (pg/ml): | 0 | 156 | 312 | 625 | 1250 | 2500 | 5000 | 10000 |
O.D.: | 0.033 | 0.055 | 0.111 | 0.207 | 0.399 | 0.735 | 1.251 | 2.029 |
Review