Overview
Properties
Sensitivity: | < 10 pg/ml |
Storage Instructions: | Store at 4˚C for 1 month, at -20˚C for up to longer storage. Avoid multiple freeze/thaw cycles (Shipped with blue ice.) |
Kit Components
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Material Required But Not Provided
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Background
Gene Name: | Kallistatin |
Background: | Serpin peptidase inhibitor, clade A (alpha - 1 antiproteinase, antitrypsin), member 4, also called Kallistatin, is a protein that in humans is encoded by the SERPINA4 gene. This gene is mapped to chromosome 14q32.13. Kallistatin is a serine proteinase inhibitor (serpin) and a heparin - binding protein. It is localized in vascular smooth muscle cells and endothelial cells of blood vessels, suggesting that it may be involved in the regulation of vascular function. It shows that kallistatin plays a role in neointima hyperplasia. The potential role of kallistatin was investigated in angiogenesis in vitro and in vivo, and presented results demonstrating a novel role of the protein in the inhibition of angiogenesis and tumor growth. |
Synonym: | KAIN_HUMAN; Kallikrein inhibitor; Kallistatin; Peptidase inhibitor 4; PI - 4; PI4; Serpin A4; SERPINA4 |
NCBI Gene ID: | 5267 |
UniProt ID: | P29622 |
Intra/Inter Assay Precision
Intra | Inter | |||||
Sample: | 1 | 2 | 3 | 1 | 2 | 3 |
n: | 16 | 16 | 16 | 24 | 24 | 24 |
Mean (pg/ml): | 1521 | 3786 | 6866 | 1637 | 4242 | 7128 |
Standard deviation: | 77.6 | 170.4 | 425.7 | 104.8 | 237.6 | 499 |
CV (%): | 5.1 | 4.5 | 6.2 | 6.4 | 5.6 | 7 |
Typical Data
Concentration (pg/ml): | 0 | 156 | 312 | 625 | 1250 | 2500 | 5000 | 10000 |
O.D.: | 0.067 | 0.125 | 0.175 | 0.280 | 0.450 | 0.848 | 1.489 | 2.153 |
Images
Human Kallistatin/Serpina4 ELISA Kit standard curve |
Review