Overview
| Product Name: | test |
| Catalog No: | CUBTEST001 |
| Description: | test test test test test |
| Species Reactivity: | Human; Mouse; Rat |
| Tested Applications: | WB; IHC; IF |
| Clonality: | Polyclonal |
| Immunogen: | Peptide sequence around phosphorylation site of serine 58 (R-S-S(p)-W-R) derived from Human 14-3-3 zeta. |
| Source Species: | Rabbit |
Properties
| Form: | Liquid |
| Storage Buffer: | Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instructions: | Store at -20°C |
Recommended Dilutions/Amounts
| WB: | 1/500 - 1/1000 IHC |
Background
| Background: | This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. [provided by RefSeq, Oct 2008] |
| Synonym: | HEL4; YWHAD; KCIP-1; HEL-S-3; HEL-S-93; 14-3-3-zeta |
| NCBI Gene ID: | 7534 |
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Review