Vitamin D Receptor (Phospho Ser208) Antibody (CUBAB01628)

Product Name: Vitamin D Receptor (Phospho Ser208) Antibody
Catalog No: CUBAB01628

Rabbit polyclonal antibody Vitamin D Receptor (Phospho Ser208) antibody. Tested by: WB, . Reactive for: human.

Quantity: 100 μg
Species Reactivity: Human
Tested Applications: WB;
Clonality: Polyclonal
Immunogen: Peptide sequence around phosphorylation site of serine 208 (A-L-S(p)-P-V) derived from Human Vitamin D Receptor.
Source Species: Rabbit
Form: Liquid
Storage Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Instructions: Store at -20°C
Concentration: 1.0 mg/mL
Recommended Dilutions/Amounts
WB: 1/500 - 1/1000

This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Feb 2011]

Synonym: NR1I1; PPP1R163
NCBI Gene ID: 7421

  1. Influence of single nucleotide polymorphisms of vitamin D receptor-gene on the level of osteoassociated hormones linkage with postmenopausal osteoporosis. Ziablitsev DS, et al. Fiziol Zh, 2015. PMID 26845840
  2. Vitamin D Receptor Gene FokI Polymorphism Contributes to Increasing the Risk of Tuberculosis: An Update Meta-Analysis. Huang L, et al. Medicine (Baltimore), 2015 Dec. PMID 26705207 Free PMC Article
  3. [Association of vitamin D receptor gene polymorphisms with mild cognitive impairment among elderly ethnic Uygurs]. Zhou X, et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi, 2015 Dec. PMID 26663069
  4. Association Between Vitamin D Receptor rs731236 (Taq1) Polymorphism and Risk for Restless Legs Syndrome in the Spanish Caucasian Population. Jim??nez-Jim??nez FJ, et al. Medicine (Baltimore), 2015 Nov. PMID 26632733
  5. 1??,25-Dihydroxyvitamin D3 Regulates Mitochondrial Oxygen Consumption and Dynamics in Human Skeletal Muscle Cells. Ryan ZC, et al. J Biol Chem, 2016 Jan 15. PMID 26601949
  6. Cloning and expression of full-length cDNA encoding human vitamin D receptor.
    Baker A.R., McDonnell D.P., Hughes M., Crisp T.M., Mangelsdorf D.J., Haussler M.R., Pike J.W., Shine J., O'Malley B.W.
    Proc. Natl. Acad. Sci. U.S.A. 85:3294-3298(1988) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
  7. A single receptor identical with that from intestine/T47D cells mediates the action of 1,25-dihydroxyvitamin D-3 in HL-60 cells.
    Goto H., Chen K.S., Prahl J.M., Deluca H.F.
    Biochim. Biophys. Acta 1132:103-108(1992) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
  8. Rae J.L., Shepard A.R.
    Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databasesCited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1). Tissue: Lens epithelium.
  9. Structural organization of the human vitamin D receptor chromosomal gene and its promoter.
    Miyamoto K., Kesterson R.A., Yamamoto H., Taketani Y., Nishiwaki E., Tatsumi S., Inoue Y., Morita K., Takeda E., Pike J.W.
    Mol. Endocrinol. 11:1165-1179(1997) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  10. NIEHS SNPs program
    Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databasesCited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANTS VAL-230 AND ILE-362.

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Cat No.: CUBAB01628
Size Price
100 μl $298.00
Shipping info


Antibodies, Proteins, ELISA Kits: 5 to 10 Business Days, Ambient (unless otherwise required*)
*Based on stability testing and to save packing waste, most antibodies will be shipped at ambient temperature.

Cells: 2 to 3 Days, Dry Ice.


Ambient:  $25

Blue Ice/Ice Packs:  $45 (As Required or Upon request)

Dry Ice: $55



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